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1

Gallstones

Lammert, Frank, Gurusamy, Kurinchi, Ko, Cynthia W., Miquel, Juan-Francisco, Méndez-Sánchez, Nahum, Portincasa, Piero, van Erpecum, Karel J., van Laarhoven, Cees J., Wang, David Q.-H.

Journal:

Nature Reviews Disease Primers

Year:

2016

Language:

english

File:

PDF, 9.95 MB

english, 2016

2

Coordinate regulation of gallbladder motor function in the gut-liver axis

Piero Portincasa, Agostino Di Ciaula, Helen H. Wang, Giuseppe Palasciano, Karel J. van Erpecum, Antonio Moschetta, David Q.-H. Wang

Journal:

Year:

2008

Language:

english

File:

PDF, 453 KB

english, 2008

3

Complications of bile-duct stones: acute cholangitis and pancreatitis

Karel J. van Erpecum

Journal:

Best Practice & Research Clinical Gastroenterology

Year:

2006

Language:

english

File:

PDF, 476 KB

english, 2006

4

Probiotics in primary sclerosing cholangitis: a randomized placebo-controlled crossover pilot study

Vleggaar, Frank P., Monkelbaan, Jan F., van Erpecum, Karel J.

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2008

Language:

english

File:

PDF, 97 KB

english, 2008

5

Ursodeoxycholic acid exerts no beneficial effect in patients with symptomatic gallstones awaiting cholecystectomy

Niels G. Venneman, Marc G.H. Besselink, Yolande C.A. Keulemans, Gerard P. vanBerge-Henegouwen, Marja A. Boermeester, Ivo A.M.J. Broeders, Peter M.N.Y.H. Go, Karel J. van Erpecum

Journal:

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

6

Improved Prognosis of Patients With Primary Biliary Cirrhosis That Have a Biochemical Response to Ursodeoxycholic Acid

Edith M.M. Kuiper, Bettina E. Hansen, Richard A. de Vries, Jannie W. den Ouden–Muller, Theo J.M. van Ditzhuijsen, Els B. Haagsma, Martin H.M.G. Houben, Ben J.M. Witteman, Karel J. van Erpecum, Henk R.

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 837 KB

english, 2009

7

Randomized Controlled Trials of Antibiotic Prophylaxis in Severe Acute Pancreatitis: Relationship between Methodological Quality and Outcome

de Vries, Annemarie C., Besselink, Marc G.H., Buskens, Erik, Ridwan, Ben U., Schipper, Maria, van Erpecum, Karel J., Gooszen, Hein G.

Journal:

Year:

2007

Language:

english

File:

PDF, 127 KB

english, 2007

8

Natural history and treatment of Hepatitis C/HIV coinfection: is it time to change paradigms?

Arends, Joop E., Lieveld, Faydra, Boeijen, Lauke L., de Kanter, Clara T.M.M., van Erpecum, Karel J., Salmon, Dominique, Hoepelman, Andy I.M., Asselah, Tarik, Ustianowski, Andrew

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 649 KB

english, 2015

9

Radioembolization-induced liver disease

Braat, Manon N.G.J.A., van Erpecum, Karel J., Zonnenberg, Bernard A., van den Bosch, Maurice A.J., Lam, Marnix G.E.H.

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2017

Language:

english

File:

PDF, 241 KB

english, 2017

10

Liver decompensation in HIV/Hepatitis B coinfection in the cART era does not seem increased compared to hepatitis B mono-infection

Lieveld, Faydra I., Smit, Colette, Richter, Clemens, van Erpecum, Karel J., Spanier, Bernhard W.M., Gisolf, Elisabeth H., Vrolijk, Jan M., Siersema, Peter D., Hoepelman, Andy I.M., Reiss, Peter, Arend

Journal:

Liver International

Year:

2018

Language:

english

File:

PDF, 1.13 MB

english, 2018

11

Relevance of interactions between sphingomyelin and cholesterol in biliary and intestinal tract

Karel J. van Erpecum, Michele Petruzzelli, Albert K. Groen, Antonio Moschetta

Journal:

European Journal of Lipid Science and Technology

Year:

2007

Language:

english

File:

PDF, 136 KB

english, 2007

12

Effects of Aramchol on in vitro bile cholesterol crystallization and bile acid detergency

Gijs J. de Bruin, Michele Petruzzelli, Niels G. Venneman, L. Paul van Minnen, Piero Portincasa, Fred M. Konikoff, Karel J. van Erpecum

Journal:

European Journal of Lipid Science and Technology

Year:

2008

Language:

english

File:

PDF, 533 KB

english, 2008

13

Bile concentration is a key factor for nucleation of cholesterol crystals and cholesterol saturation index in gallbladder bile of gallstone patients

Karel J. Van Erpecum, Gerard P. Berge Van Henegouwen, Bregt Stoelwinder, Yvonne M. G. Schmidt, Frans L. H. Willekens

Journal:

Year:

1990

Language:

english

File:

PDF, 532 KB

english, 1990

14

The effects of the 3-hydroxy, 3-methylglutaryl coenzyme a reductase inhibitor pravastatin on bile composition and nucleation of cholesterol crystals in cholesterol gallstone disease

Jan W. A. Smit, Karel J. Van Erpecum, Willem Renooij, Mark F. J. Stolk, Patrick Edgar, Heleen Doornewaard, Gerard P. Vanberge-Henegouwen

Journal:

Year:

1995

Language:

english

File:

PDF, 800 KB

english, 1995

15

Small gallstones, preserved gallbladder motility, and fast crystallization are associated with pancreatitis

Niels G. Venneman, Willem Renooij, Jens F. Rehfeld, Gerard P. vanBerge-Henegouwen, Peter M. N. Y. H. Go, Ivo A. M. J. Broeders, Karel J. van Erpecum

Journal:

Year:

2005

Language:

english

File:

PDF, 208 KB

english, 2005

16

Reply:

Niels G. Venneman, Karel J. van Erpecum

Journal:

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

17

Nasobiliary drainage induces long-lasting remission in benign recurrent intrahepatic cholestasis

Janneke M. Stapelbroek, Karel J. van Erpecum, Leo W. J. Klomp, Niels G. Venneman, Thijs P. Schwartz, Gerard P. van Berge Henegouwen, John Devlin, Carin M. J. van Nieuwkerk, A. S. Knisely, Roderick H.

Journal:

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

18

Long-term exclusive zinc monotherapy in symptomatic Wilson disease: Experience in 17 patients

Francisca H. H. Linn, Roderick H. J. Houwen, Jan van Hattum, Stefan van der Kleij, Karel J. van Erpecum

Journal:

Year:

2009

Language:

english

File:

PDF, 437 KB

english, 2009

19

Reply: Adjunctive vitamin E treatment in Wilson disease and suggestions for future trials

Roderick H. J. Houwen, Francisca H. H. Linn, Karel J. van Erpecum

Journal:

Year:

2010

Language:

english

File:

PDF, 168 KB

english, 2010

20

The potent bile acid sequestrant colesevelam is not effective in cholestatic pruritus: Results of a double-blind, randomized, placebo-controlled trial

Edith M. M. Kuiper, Karel J. van Erpecum, Ulrich Beuers, Bettina E. Hansen, H. Bing Thio, Robert A. de Man, Harry L. A. Janssen, Henk R. van Buuren

Journal:

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

21

Cholesterol crystallization in human gallbladder bile: Relation to gallstone number, bile composition, and apolipoprotein E4 isoform

Karel J. Van Erpecum, Gerard P. Van Berge-Henegouwen, Erik R.M. Eckhardt, Piero Portincasa, Bert J.M. Van De Heijning, Geesje M. Dallinga-Thie, Albert K. Groen

Journal:

Year:

1998

Language:

english

File:

PDF, 137 KB

english, 1998

22

Gallstone disease: primary and secondary prevention

Niels G. Venneman, Karel J. van Erpecum

Journal:

Best Practice & Research Clinical Gastroenterology

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

23

Timing of cholecystectomy after endoscopic sphincterotomy for common bile duct stones

Anandi H. W. Schiphorst, Marc G. H. Besselink, Djamila Boerma, Robin Timmer, Marinus J. Wiezer, Karel J. van Erpecum, Ivo A. M. J. Broeders, Bert van Ramshorst

Journal:

Surgical Endoscopy

Year:

2008

Language:

english

File:

PDF, 188 KB

english, 2008

24

Is Complicated Gallstone Disease Preceded by Biliary Colic?

Marc G. Besselink, Niels G. Venneman, Peter M. Go, Ivo A. Broeders, Peter D. Siersema, Hein G. Gooszen, Karel J. van Erpecum

Journal:

Journal of Gastrointestinal Surgery

Year:

2009

Language:

english

File:

PDF, 129 KB

english, 2009

25

Biliary Colic is a Valuable Clinical Descriptor for Biliary Pain Due to “Uncomplicated” Gallstone Disease

Marc G. H. Besselink, Karel J. van Erpecum

Journal:

Journal of Gastrointestinal Surgery

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

26

Minimally invasive image-guided therapy for inoperable hepatocellular carcinoma: What is the evidence today?

Beatrijs A. Seinstra, Otto M. van Delden, Karel J. van Erpecum, Richard van Hillegersberg, Willem P. Th. M. Mali, Maurice A. A. J. van den Bosch

Journal:

Insights into Imaging

Year:

2010

Language:

english

File:

PDF, 552 KB

english, 2010

27

Preface

Karel J. van Erpecum, Piero Portincasa

Journal:

Best Practice & Research Clinical Gastroenterology

Year:

2006

Language:

english

File:

PDF, 34 KB

english, 2006

28

Intestinal mucosal damage caused by non-steroidal anti-inflammatory drugs: Role of bile salts

Michele Petruzzelli, Michele Vacca, Antonio Moschetta, Rosa Cinzia Sasso, Giuseppe Palasciano, Karel J. van Erpecum, Piero Portincasa

Journal:

Clinical Biochemistry

Year:

2007

Language:

english

File:

PDF, 469 KB

english, 2007

29

The natural history of childhood-acquired hepatitis C infection in patients with inherited bleeding disorders

Dirk Posthouwer, Kathelijn Fischer, Karel J. Van Erpecum, Eveline P. Mauser-Bunschoten

Journal:

Transfusion (Wiley)

Year:

2006

Language:

english

File:

PDF, 111 KB

english, 2006

30

Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease

Kirsten Boonstra, Karel J. van Erpecum, Karin M.J. van Nieuwkerk, Joost P.H. Drenth, Alexander C. Poen, Ben J.M. Witteman, Hans A.R.E. Tuynman, Ulrich Beuers, Cyriel Y. Ponsioen

Journal:

Inflammatory Bowel Diseases

Year:

2012

Language:

english

File:

PDF, 661 KB

english, 2012

31

T-cell responses at baseline and during therapy with peginterferon-α and ribavirin are not associated with outcome in chronic hepatitis C infected patients

Joop E. Arends, Mark A.A. Claassen, Charlotte H.S.B. van den Berg, Nening M. Nanlohy, Karel J. van Erpecum, Bert C. Baak, Andy I.M. Hoepelman, Andre Boonstra, Debbie van Baarle

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

32

Micellar lipid composition profoundly affects LXR-dependent cholesterol transport across CaCo2 cells

Michele Petruzzelli, Albert K. Groen, Karel J. van Erpecum, Carlos Vrins, Astrid E. van der Velde, Piero Portincasa, Giuseppe Palasciano, Gerard P. van Berge Henegouwen, Giuseppe Lo Sasso, Annalisa Mo

Journal:

Year:

2009

Language:

english

File:

PDF, 514 KB

english, 2009

33

Cholesterol-gallstone formation: More than a biliary lipid defect?

Karel J. van Erpecum

Journal:

Journal of Laboratory and Clinical Medicine

Year:

2004

Language:

english

File:

PDF, 76 KB

english, 2004

34

The gallbladder: Innocent bystander or major factor in cholesterol-gallstone formation?

Karel J. Van Erpecum, David Q.-H. Wang

Journal:

Journal of Laboratory and Clinical Medicine

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

35

Quantifying vesicle/mixed micelle partitioning of phosphatidylcholine in model bile by using radiolabeled phosphatidylcholine species

Willem Renooij, Petra J. van Gaal, Karel J. van Erpecum, Bert J.M. Van De Heijning, Gerard P. Van Berge Henegouwen

Journal:

Journal of Laboratory and Clinical Medicine

Year:

1996

Language:

english

File:

PDF, 616 KB

english, 1996

36

Bacterial infections in cirrhosis: role of proton pump inhibitors and intestinal permeability

Lotte G. van Vlerken, Ellen J. Huisman, Bart van Hoek, Willem Renooij, Felix W. M. de Rooij, Peter D. Siersema, Karel J. van Erpecum

Journal:

European Journal of Clinical Investigation

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

37

Serum autotaxin is increased in pruritus of cholestasis, but not of other origin, and responds to therapeutic interventions

Andreas E. Kremer, Remco van Dijk, Pamela Leckie, Frank G. Schaap, Edith M.M. Kuiper, Thomas Mettang, Katrin S. Reiners, Ulrike Raap, Henk R. van Buuren, Karel J. van Erpecum, Nathan A. Davies, Christ

Journal:

Year:

2012

Language:

english

File:

PDF, 897 KB

english, 2012

38

The effects of bile salt hydrophobicity on model bile vesicle morphology

Bert J.M. van de Heijning, Mark F.J. Stolk, Karel J. van Erpecum, Willem Renooij, Gerard P. van Berge Henegouwen

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1994

Language:

english

File:

PDF, 1.10 MB

english, 1994

39

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine

Raffaella M. Gadaleta, Bas Oldenburg, Ellen C.L. Willemsen, Maureen Spit, Stefania Murzilli, Lorena Salvatore, Leo W.J. Klomp, Peter D. Siersema, Karel J. van Erpecum, Saskia W.C. van Mil

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 817 KB

english, 2011

40

Effects of hydrophobic and hydrophilic bile salts on gallstone growth and dissolution in model biles

Niels G. Venneman, Marieke van Kammen, Willem Renooij, Gerard P. vanBerge-Henegouwen, Karel J. van Erpecum

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2005

Language:

english

File:

PDF, 551 KB

english, 2005

41

Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease

Raffaella M. Gadaleta, Saskia W.C. van Mil, Bas Oldenburg, Peter D. Siersema, Leo W.J. Klomp, Karel J. van Erpecum

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 958 KB

english, 2010

42

Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms

Danielle A.A. Hollman, Alexandra Milona, Karel J. van Erpecum, Saskia W.C. van Mil

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2012

Language:

english

File:

PDF, 962 KB

english, 2012

43

The H1069Q mutation in ATP7B is associated with late and neurologic presentation in Wilson disease: results of a meta-analysis

Janneke M. Stapelbroek, Casper W. Bollen, Johannes K. Ploos van Amstel, Karel J. van Erpecum, Jan van Hattum, Leonard H. van den Berg, Leo W.J. Klomp, Roderick H.J. Houwen

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 110 KB

english, 2004

44

Liver disease associated with canalicular transport defects: Current and future therapies

Janneke M. Stapelbroek, Karel J. van Erpecum, Leo W.J. Klomp, Roderick H.J. Houwen

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 1015 KB

english, 2010

45

Preventive versus “on-demand” nutritional support during antiviral treatment for hepatitis C: A randomized controlled trial

Ellen J. Huisman, Bart van Hoek, Hanneke van Soest, Karin M. van Nieuwkerk, Joop E. Arends, Peter D. Siersema, Karel J. van Erpecum

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 913 KB

english, 2012

46

Influence of bile salts on molecular interactions between sphingomyelin and cholesterol: relevance to bile formation and stability

Karel J van Erpecum, Martin C Carey

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1997

Language:

english

File:

PDF, 381 KB

english, 1997

47

Biliary pronucleating proteins and apolipoprotein E in cholesterol and pigment stone patients

Karel J van Erpecum, Piero Portincasa, Mehmet H Dohlu, Gerard P van Berge-Henegouwen, Dieter Jüngst

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 192 KB

english, 2003

48

Accurate separation of vesicles, micelles and cholesterol crystals in supersaturated model biles by ultracentrifugation, ultrafiltration and dialysis

Antonio Moschetta, Erik R.M Eckhardt, Martin B.M De Smet, Willem Renooij, Gerard P Van Berge-Henegouwen, Karel J Van Erpecum

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2001

Language:

english

File:

PDF, 491 KB

english, 2001

49

Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles

Niels G Venneman, Sebastiaan J Huisman, Antonio Moschetta, Gerard P vanBerge-Henegouwen, Karel J van Erpecum

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2002

Language:

english

File:

PDF, 269 KB

english, 2002

50

Different interactions of egg-yolk phosphatidylcholine and sphingomyelin with detergent bile salts

Catharina P Nibbering, Peter M Frederik, Gerard P van Berge-Henegouwen, Henk A van Veen, Jan van Marle, Karel J van Erpecum

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2002

Language:

english

File:

PDF, 352 KB

english, 2002

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